As the Cannabis market grows for medical and recreational use, so does the requirement for standardized quality control in the industry. With regards to Cannabis quality control there are many things to consider, from moisture content to pesticide use.
Moisture Content – Cannabis flower moisture content should be tested and controlled to: minimize the risk of mold formation; control microbiological levels; ensure proper drying, curing and storage conditions; and support product life expectancy. Some manufacturing processes for cannabis quality assurance plan also need a certain water content in the starting material.
Terpenoids and Cannabinoids Analysis
The level of terpenoids and cannabinoids inside the starting material determines the most appropriate industrial processing method and which final cannabis product is going to be manufactured. This analysis is normally completed using LC-MS (Liquid Chromatography Mass Spectrometry) or GC (Gas Chromatography). LC-MS and GC demand a flow of inert gas such as hydrogen or nitrogen, each of which can easily be supplied using a gas generator. Discover more concerning the Peak Scientific variety of gas generators for GC & LC-MS here.
Pesticides and Herbicides – As with other agricultural crops and products designed for human consumption, Cannabis plants should be tested for herbicides and pesticides. Detecting pesticides and herbicides can be difficult because of the complexity of cannabis material. GCMS (Gas Chromatography Mass Spectrometry) is usually used for this specific purpose.
Microbiological Screening – Medical Cannabis is usually utilized for HIV and cancer patients where patient’s defense mechanisms continues to be compromised. Therefore, high microbial levels or pathogenic micro-organisms may be life threatening. It is important then that several Mycotoxins and fungus types should be detected as an element of cannabis quality control and release specifications.
Residual Solvents – Where solvents happen to be used included in Cannabis product processing, solvent residuals inside the final products ought to be tested to make sure that they fulfill the accepted criteria. The FDA has published zvqtob criteria for residual solvents in APIs for pharmaceutical use.
Chemical Toxins – Like many other plants, Cannabis draws metals from your earth. It really is therfore required to test for Mercury, Lead, Arsen and Cadmium.
Cannabinoid Concentration – Concentration ranges for cannabinoids including THC,THCa, CBD, CBDa, CBN, CBC, CBG should match the ranges specified on the product label, according to product usage purpose, patient’s medical condition, age etc. Cannabinoid concentrations can be tested using LC-MS (Liquid Chromatography Mass Spectrometry) and HPLC (Good Performance Liquid Chromatography) . There are a wide range of Peak Scientific nitrogen gas generators designed particularly for LC-MS, available here.
Terpene Concentration – Terpenes increase cannabinoids’ therapeutic effects and are known to get their own health benefits, additionally they play a role in Cannabis taste and aroma. They could be detected using GC.
Taking all of the above into consideration, it is clear that there is a necessity for standarized procedures for all the Cannabis analysis and testing process to be able to guarantee safe use. The safest way to supply cannabis testing laboratories with gas for his or her LC-MS and GC is via gas generators, which tend not to present the safety and health risks related to gas cylinders.