Our bodies consist of many unique physiologic systems whose sole purpose would be to maintain an internal balance called homeostasis. We know the pancreas releases insulin to balance blood sugar levels between the bloodstream and cells. The thyroid gland releases thyroid hormone, which regulates vital bodily processes related to metabolism, body temperature plus much more. In other words, the body are working constantly to stay balanced in response to our external environment.
Inside the quest to know the way THC causes its popular intoxicating effects, scientists learned that we have one more regulatory physiologic system, called the endocannabinoid system (ECS), whose role is always to maintain homeostasis of the messages sent between our cells. Further research has revealed that sickness, inflammation, and injury will trigger the ECS to consider action, trying to reset our internal environment back to homeostasis. This method continues to be referred to as being protective and necessary for life. Imagine if we could target this technique to stop illness and keep better health?
Endocannabinoids, also known as our “inner cannabis,” are synthesized at will from healthy sources of dietary fat. Cannabinoid receptors sit on the membranes of cells in some elements of the mind and the body, namely areas within the brain that control pain, memory, emotion, motor control, nausea, and appetite, along with the gut, immunity mechanism, and peripheral central nervous system. If you have a trigger that triggers an imbalance, like a physical injury or illness, endocannabinoids are released, acting as “keys” that bind towards the receptors, which work as “locks” on our cells. After the receptor is activated, a chemical reaction happens in the cell, telling the cell to alter its message.
ECS functioning is dependent upon many factors, including genetics, age, levels of stress, diet, and overall level of health. There might be variants inside the genes that code for the ECS which can cause propensities for several conditions, including ADHD and PTSD. Additionally, chronic illness, chronic stress or chronic sleep deprivation can lead to depletion from the endocannabinoids. These disruptions within the normal functioning of the ECS hinder its ability to regulate cellular imbalances and achieve homeostasis.
In 2004, Ethan Russo, a neurologist and research scientist, published Clinical endocannabinoids Deficiency (CECD): Can this concept explain therapeutic advantages of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? within the journal Neuroendocrinology Letters. Russo theorized that certain people with the listed conditions responded to cannabis-based treatments because they had endocannabinoid deficiencies that allowed the disorder to manifest in the first place.
Subsequent reports have demonstrated that endocannabinoid deficiency plays a part in autoimmune diseases, epilepsy, complex regional pain syndrome, heart disease, depression, anxiety, schizophrenia, multiple sclerosis, nausea, Huntington’s disease, Parkinson’s disease, menstrual symptoms, failure to thrive in newborns, along with other difficult-to-treat conditions.
The cannabis plant produces over 100 phytocannabinoids, including tetrahydrocannabinol (THC) and cannabidiol (CBD). These compounds mimic the endocannabinoids by interacting with the ECS and restoring homeostasis. Instead of delay until illness exists, there are numerous approaches to take better care of your ECS, that can allow it to function properly, avoid deficiencies and keep homeostasis.
It’s common knowledge that a healthy, balanced eating habits are necessary for emotional and physical well-being. The body count on our diet to generate the correct quantity of endocannabinoids to function at optimal capacity. Cannabinoids are synthesized through the fatty acids within our diets and need a specific balance of omega-6 and omega-3 to be produced in the correct quantities.
For max bioavailability, the perfect ratio of omega-6 to omega-3 essential fatty acids from food is between 5:1 and 1:1, the low the better for all those with chronic illness. Western diets routinely consist of ratios of 20:1, mainly as a result of overconsumption of omega-6 fatty acids which result from vegetable oils in lots of packaged foods. Western diets with higher ratios of omega-6 to omega-3 fatty acids results in a decrease in endocannabinoids, resulting in the lack of ability to maintain homeostasis.
Another thing that promotes well-being from the ECS is aerobic exercise. Animal studies are convinced that voluntary wheel running increases cannabinoid receptors in the brain and boosts the sensitivity in the receptors to endocannabinoids. Human research indicates that exercise including running, biking and hiking enhance endocannabinoid levels in the bloodstream. In fact, endocannabinoids are likely in charge of the phenomenon described as the “runner’s high.”
Probiotics may also help the ECS. Lactobacillus acidophilus, a probiotic bacteria present in fermented foods including yogurt and sauerkraut, was shown to induce the expression of cannabinoid receptors inside the gut, promoting intestinal homeostasis.
Both acupuncture and osteopathic manipulation enhance the ECS. Yoga and meditation elicit the “relaxation response,” a physiological wjeflf phenomenon whereby one can consciously participate in behavior that promotes physical and mental wellness; although no studies have been done to date, most experts suspect these stress management modalities improve the ECS thereby promoting homeostasis.
Lastly, how about the capability of cannabis to avoid illness? Plant cannabinoids are-known to be safe as well as have anti-inflammatory, antioxidant and neuroprotective properties. In cases of endocannabinoid deficiency, cannabis use could be the correcting compound, eliminating the signs and symptoms of the disorder. Regular cannabis use can decrease chronic inflammation and buildup of free radicals, each of which are thought to be the basis reasons for many conditions, including autoimmune and neurodegenerative disorders.